Automatic system updates with mobile data

E-FOTA works next to an existing MDM solution, so yes it will work with your MDM as well. When enrolling new devices, make sure to have a Knox E-FOTA campaign assigned to them in the Knox portal. If thats done, devices will recieve E-FOTA automaticly, you don't need to push an app or permissions. 

When deploying E-FOTA to existing hardware without resetting them, you have to push the app and set some permissions (if possible, use the Knox Service plugin for setting FOTA permissions: https://docs.samsungknox.com/admin/knox-platform-for-enterprise/knox-service-plugin/get-started/minimum-requirements/)

E-FOTA is developed by Samsung, all tough they share some API's with other vendors they do not share all of them. E-FOTA is such a that only works via their portal, the API it utilizes is not available for others.